Magnesium Threonate for Focus and Sleep: Brain-Available Magnesium, Calm Nights, Daily Dosing
Overview
Magnesium Threonate is used for calm focus by day and easier wind down at night. Many choose it when they want a brain-available magnesium for busy work blocks, study phases, or when sleep feels shallow.
For a general overview of forms and dosing, see Magnesium.
From mineral to brain support: what Magnesium Threonate is and how it works
This form binds magnesium to L-threonic acid. It is designed to be well tolerated and to support brain magnesium levels, which help regulate nerve signaling, stress response, and sleep quality.
What you may notice when you try Magnesium Threonate
Calm focus
Some users report steadier attention and less mental noise for reading or deep work.
Evening wind down
Taken later in the day, many describe a smoother slide into sleep and fewer night awakenings.
Stress feel
A less reactive, more collected feel across busy evenings.
How to test it for two weeks
Take it at the same time daily. Daytime for focus, or 1 to 2 hours before bed for sleep.
Track focus blocks, sleep onset, awakenings, and next-day feel.
Keep caffeine, screens, and bedtime steady so changes are clearer.
If stools loosen or you feel groggy on waking, lower the dose or move it earlier.
Safety, dosing and who should skip it
Typical dosing
Most labels provide about 1.5 to 2 g magnesium threonate complex per day, which equals roughly 100 to 150 mg elemental magnesium. Check your label for the elemental amount.
Side effects
Usually mild. Possible drowsiness, light headed feel, or GI upset at higher elemental doses. Split dosing if sensitive.
Drug interactions
Separate by 2 to 4 hours from levothyroxine, tetracycline/quinolone antibiotics, and bisphosphonates. If you use heart rhythm meds or have low blood pressure, check with a clinician.
Product quality
Choose third-party tested products that list form and elemental magnesium per serving. Avoid proprietary blends that hide the elemental amount.
Who should avoid it
Use caution starting on your own if you
have kidney disease or are on dialysis
are pregnant or breastfeeding without guidance
develop persistent diarrhea, dizziness, or palpitations after dosing
If that happens, pause and reassess.





