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Cortisol (PM): Evening Stress Hormone, Sleep Signal, and What High or Low Means

Nov 20, 2025

Nov 20, 2025

Metabolic Health

Metabolic Health

Recovery & Performance

Recovery & Performance

Stress & Adrenal

Stress & Adrenal

Metabolic Health

8 min read

8 min read

8 min read time

Overview

Hormones & Endocrine
Hormones & Endocrine

Cortisol (PM) measures your cortisol level later in the day, when it should be trending low. It is used to check whether your stress hormone rhythm is tapering like it should as evening approaches. A higher than expected PM cortisol can show up with chronic stress, sleep disruption, certain medications, or endocrine conditions. A lower than expected value can show up when adrenal output is suppressed or when timing and context matter. In this glossary you will see what PM cortisol reflects, how it compares with Cortisol (AM), how brain signaling through Adrenocorticotropic Hormone (ACTH) fits in, what can push PM cortisol off track, and how lifestyle levers like a Circadian Rhythm Reset often relate to the bigger picture.

Cortisol blood test tube with adrenal gland model and clock at night.
Cortisol blood test tube with adrenal gland model and clock at night.
Cortisol blood test tube with adrenal gland model and clock at night.
Cortisol blood test tube with adrenal gland model and clock at night.

What evening cortisol is and why it matters

Cortisol is made by your adrenal glands and follows a daily rhythm. In a typical pattern:

  • Cortisol is highest in the early morning to help you wake up and mobilize energy

  • It gradually declines through the day

  • It reaches its lowest levels at night to support winding down and sleep

Cortisol (PM) is a blood test taken in the afternoon or evening to capture that lower phase. It helps show whether the system is tapering normally or staying unusually elevated late in the day.

Because cortisol is so tied to time, a PM value is only meaningful if the draw time is clear and consistent, and if you interpret it alongside morning cortisol and symptoms.

What your Cortisol (PM) result can tell you

Your PM cortisol value can help answer questions like:

  • Is my cortisol rhythm shutting down properly by evening

  • Could my late day wired feeling, insomnia, or night waking have a stress hormone component

  • Does my cortisol pattern match stress load, training, illness, or medications

Cortisol (PM) is often used with a morning cortisol test. If morning cortisol is normal but PM cortisol stays high, it can suggest a flattened rhythm where cortisol is not tapering well. If both AM and PM cortisol are low, clinicians think about adrenal suppression or pituitary signaling issues.

How to read high and low Cortisol (PM)

PM cortisol is mostly about whether the taper looks normal.

When Cortisol (PM) is high

Higher than expected PM cortisol often means your body is not coming down into the evening the way it should. Common reasons include:

  • Chronic psychological stress, anxiety, or high life load

  • Poor sleep timing, late screens, irregular schedules, or night shift patterns

  • Overreaching training blocks with limited recovery

  • Stimulant use late in the day

  • Medications that raise cortisol or change how it is measured

  • Less commonly, endocrine conditions that push cortisol production higher

Possible effects can include trouble falling asleep, waking up at night, feeling tired but wired in the evening, and harder recovery after training. This does not automatically mean disease, but persistent high PM cortisol with symptoms is worth addressing.

When Cortisol (PM) is low

Lower PM cortisol is often normal, since evening is supposed to be low. It becomes meaningful mainly when:

  • It is low together with low morning cortisol

  • Symptoms suggest adrenal insufficiency, such as deep fatigue, low blood pressure, dizziness on standing, or low stress tolerance

  • Steroid medications have recently been used and may be suppressing cortisol output

In most cases, a low PM cortisol alone is not a problem. The pattern across the day matters more than any single evening value.

What can affect your Cortisol (PM) result

PM cortisol is sensitive to real life inputs and timing.

Common influences include:

  • Sleep schedule and circadian alignment
    Irregular bedtimes, late meals, night shift work, or poor light timing can push cortisol later into the day.

  • Stress and mental load
    High workload, relationship stress, or prolonged anxiety can keep cortisol elevated into the evening.

  • Training volume and recovery
    Hard blocks with low recovery, especially combined with under fueling, can flatten the cortisol curve and keep PM levels higher.

  • Medications and supplements
    Steroids taken in any form can suppress your own cortisol production. Some antidepressants, stimulants, and hormone products can alter levels or interpretation.

  • Illness and inflammation
    Acute infections or chronic inflammatory states can raise cortisol throughout the day as the body tries to cope.

  • Timing of the draw
    A draw at 3 p.m. and a draw at 9 p.m. are not the same signal. Consistency is key when tracking patterns.

When to talk to a clinician about Cortisol (PM)

You should review your PM cortisol with a clinician when:

  • PM cortisol is clearly high on repeat tests and you have sleep disruption, anxiety, or unexplained fatigue

  • Your AM and PM cortisol pattern looks abnormal together

  • You are taking or recently stopped steroid medications

  • Symptoms suggest adrenal insufficiency or endocrine overproduction

  • You have known pituitary or adrenal conditions

A clinician can place PM cortisol next to AM cortisol, ACTH, metabolic markers, blood pressure, medication history, and your symptom story. If needed, they can order rhythm focused testing or stimulation and suppression tests to see how the system responds, not just what a single point looks like.

Cortisol (PM) in one view

Cortisol (PM) is an evening snapshot of your main stress hormone and a check on whether your daily cortisol rhythm is tapering the way it should. High PM cortisol often reflects stress, sleep or circadian disruption, heavy training load, or medication effects, while low PM cortisol is usually normal unless the whole day pattern is low. Interpreted with morning cortisol, ACTH, and your real world symptoms, it becomes a useful guide for when recovery, sleep timing, and stress support may be enough and when deeper endocrine review is needed.

Got Questions? We've Got Answers

What exactly is Neura app?

Neura is a holistic AI health assistant that acts as your personal wellness coach. It combines your wearable data, lifestyle habits, and health metrics to deliver personalized plans, daily micro-tasks, mini-podcasts, and actionable insights to improve sleep, fitness, recovery, and longevity.

How does Neura work?

1. Answer a quick onboarding quiz (1–2 min). 2. Set your goals (e.g., better sleep, running a 5K). 3. Connect your wearables or apps for real-time health data. 4. Receive a daily, AI-personalized plan and mini-podcasts. 5. Track progress on your dashboard while Neura optimizes automatically.

Do I need a wearable or fitness tracker to use Neura?

No. You can start with just your phone and basic input. Wearables like Apple Watch, Garmin, Oura, or Fitbit unlock deeper, real-time insights and premium metrics, but they are optional.

Is my data safe and private?

Absolutely. Neura uses end-to-end encryption, is GDPR/HIPAA compliant, and gives you full control over data exports and deletion. Only anonymized data is processed for AI improvements.

What kind of results can I expect with Neura?

Most users report noticeable improvements in sleep quality, daily energy, and habit consistency within 2–3 weeks. Real-time insights help you save hours each week by replacing endless self-tracking and guesswork with an AI-driven health plan.

What devices and apps can Neura connect to?

Neura integrates with 90+ apps and devices like Apple Health, Google Fit, Garmin, Oura, Fitbit, Polar, Suunto, Peloton, Zwift, Withings, Eight Sleep, and more. You can also upload lab results for advanced analysis.

What’s included in the free plan?

The free Neura Plan comes with all the basic features you need to kickstart your holistic health and fitness journey. Those include our core AI chat (single-chat memory), a standard health plan with one active goal, up to 5 customizable Health Hub widgets, and daily auto-sync with limited integrations. Upgrade to Neura iQ for unlimited AI chat with persistent multi-session memory, multiple simultaneous Health Plans, and real-time data sync from 100+ integrations with 360° Health Sync, alongside all other premium features.

How is Neura different from other health apps or trackers?

Neura isn’t just a tracker – it’s a smart health operating system. It pulls together your data, analyzes it in real time, and gives you proactive, science-backed recommendations tailored to your lifestyle, without the hassle of manual research or multiple apps.

Can I cancel or get a refund if I’m not satisfied?

Yes. Neura Free is free forever, and Neura IQ comes with a 7-day free trial. After upgrading, you can cancel anytime. If you’re not satisfied within 30 days, we offer a full refund—no questions asked.

How do I get started with Neura?

Simply sign up with your email to claim free early access. You can start in less than 2 minutes, connect your wearables later, and immediately receive your personalized plan and first mini-podcast.

Ready to Transform
Your Health with Neura?

Don't wait, we have limited spots for the beta sign up

Got Questions? We've Got Answers

What exactly is Neura app?

Neura is a holistic AI health assistant that acts as your personal wellness coach. It combines your wearable data, lifestyle habits, and health metrics to deliver personalized plans, daily micro-tasks, mini-podcasts, and actionable insights to improve sleep, fitness, recovery, and longevity.

How does Neura work?

1. Answer a quick onboarding quiz (1–2 min). 2. Set your goals (e.g., better sleep, running a 5K). 3. Connect your wearables or apps for real-time health data. 4. Receive a daily, AI-personalized plan and mini-podcasts. 5. Track progress on your dashboard while Neura optimizes automatically.

Do I need a wearable or fitness tracker to use Neura?

No. You can start with just your phone and basic input. Wearables like Apple Watch, Garmin, Oura, or Fitbit unlock deeper, real-time insights and premium metrics, but they are optional.

Is my data safe and private?

Absolutely. Neura uses end-to-end encryption, is GDPR/HIPAA compliant, and gives you full control over data exports and deletion. Only anonymized data is processed for AI improvements.

What kind of results can I expect with Neura?

Most users report noticeable improvements in sleep quality, daily energy, and habit consistency within 2–3 weeks. Real-time insights help you save hours each week by replacing endless self-tracking and guesswork with an AI-driven health plan.

What devices and apps can Neura connect to?

Neura integrates with 90+ apps and devices like Apple Health, Google Fit, Garmin, Oura, Fitbit, Polar, Suunto, Peloton, Zwift, Withings, Eight Sleep, and more. You can also upload lab results for advanced analysis.

What’s included in the free plan?

The free Neura Plan comes with all the basic features you need to kickstart your holistic health and fitness journey. Those include our core AI chat (single-chat memory), a standard health plan with one active goal, up to 5 customizable Health Hub widgets, and daily auto-sync with limited integrations. Upgrade to Neura iQ for unlimited AI chat with persistent multi-session memory, multiple simultaneous Health Plans, and real-time data sync from 100+ integrations with 360° Health Sync, alongside all other premium features.

How is Neura different from other health apps or trackers?

Neura isn’t just a tracker – it’s a smart health operating system. It pulls together your data, analyzes it in real time, and gives you proactive, science-backed recommendations tailored to your lifestyle, without the hassle of manual research or multiple apps.

Can I cancel or get a refund if I’m not satisfied?

Yes. Neura Free is free forever, and Neura IQ comes with a 7-day free trial. After upgrading, you can cancel anytime. If you’re not satisfied within 30 days, we offer a full refund—no questions asked.

How do I get started with Neura?

Simply sign up with your email to claim free early access. You can start in less than 2 minutes, connect your wearables later, and immediately receive your personalized plan and first mini-podcast.

Ready to Transform
Your Health with Neura?

Don't wait, we have limited spots for the beta sign up

Got Questions? We've Got Answers

What exactly is Neura app?

Neura is a holistic AI health assistant that acts as your personal wellness coach. It combines your wearable data, lifestyle habits, and health metrics to deliver personalized plans, daily micro-tasks, mini-podcasts, and actionable insights to improve sleep, fitness, recovery, and longevity.

How does Neura work?

1. Answer a quick onboarding quiz (1–2 min). 2. Set your goals (e.g., better sleep, running a 5K). 3. Connect your wearables or apps for real-time health data. 4. Receive a daily, AI-personalized plan and mini-podcasts. 5. Track progress on your dashboard while Neura optimizes automatically.

Do I need a wearable or fitness tracker to use Neura?

No. You can start with just your phone and basic input. Wearables like Apple Watch, Garmin, Oura, or Fitbit unlock deeper, real-time insights and premium metrics, but they are optional.

Is my data safe and private?

Absolutely. Neura uses end-to-end encryption, is GDPR/HIPAA compliant, and gives you full control over data exports and deletion. Only anonymized data is processed for AI improvements.

What kind of results can I expect with Neura?

Most users report noticeable improvements in sleep quality, daily energy, and habit consistency within 2–3 weeks. Real-time insights help you save hours each week by replacing endless self-tracking and guesswork with an AI-driven health plan.

What devices and apps can Neura connect to?

Neura integrates with 90+ apps and devices like Apple Health, Google Fit, Garmin, Oura, Fitbit, Polar, Suunto, Peloton, Zwift, Withings, Eight Sleep, and more. You can also upload lab results for advanced analysis.

What’s included in the free plan?

The free Neura Plan comes with all the basic features you need to kickstart your holistic health and fitness journey. Those include our core AI chat (single-chat memory), a standard health plan with one active goal, up to 5 customizable Health Hub widgets, and daily auto-sync with limited integrations. Upgrade to Neura iQ for unlimited AI chat with persistent multi-session memory, multiple simultaneous Health Plans, and real-time data sync from 100+ integrations with 360° Health Sync, alongside all other premium features.

How is Neura different from other health apps or trackers?

Neura isn’t just a tracker – it’s a smart health operating system. It pulls together your data, analyzes it in real time, and gives you proactive, science-backed recommendations tailored to your lifestyle, without the hassle of manual research or multiple apps.

Can I cancel or get a refund if I’m not satisfied?

Yes. Neura Free is free forever, and Neura IQ comes with a 7-day free trial. After upgrading, you can cancel anytime. If you’re not satisfied within 30 days, we offer a full refund—no questions asked.

How do I get started with Neura?

Simply sign up with your email to claim free early access. You can start in less than 2 minutes, connect your wearables later, and immediately receive your personalized plan and first mini-podcast.

Ready to Transform
Your Health with Neura?

Don't wait, we have limited spots for the beta sign up

Got Questions? We've Got Answers

What exactly is Neura app?

Neura is a holistic AI health assistant that acts as your personal wellness coach. It combines your wearable data, lifestyle habits, and health metrics to deliver personalized plans, daily micro-tasks, mini-podcasts, and actionable insights to improve sleep, fitness, recovery, and longevity.

How does Neura work?

1. Answer a quick onboarding quiz (1–2 min). 2. Set your goals (e.g., better sleep, running a 5K). 3. Connect your wearables or apps for real-time health data. 4. Receive a daily, AI-personalized plan and mini-podcasts. 5. Track progress on your dashboard while Neura optimizes automatically.

Do I need a wearable or fitness tracker to use Neura?

No. You can start with just your phone and basic input. Wearables like Apple Watch, Garmin, Oura, or Fitbit unlock deeper, real-time insights and premium metrics, but they are optional.

Is my data safe and private?

Absolutely. Neura uses end-to-end encryption, is GDPR/HIPAA compliant, and gives you full control over data exports and deletion. Only anonymized data is processed for AI improvements.

What kind of results can I expect with Neura?

Most users report noticeable improvements in sleep quality, daily energy, and habit consistency within 2–3 weeks. Real-time insights help you save hours each week by replacing endless self-tracking and guesswork with an AI-driven health plan.

What devices and apps can Neura connect to?

Neura integrates with 90+ apps and devices like Apple Health, Google Fit, Garmin, Oura, Fitbit, Polar, Suunto, Peloton, Zwift, Withings, Eight Sleep, and more. You can also upload lab results for advanced analysis.

What’s included in the free plan?

The free Neura Plan comes with all the basic features you need to kickstart your holistic health and fitness journey. Those include our core AI chat (single-chat memory), a standard health plan with one active goal, up to 5 customizable Health Hub widgets, and daily auto-sync with limited integrations. Upgrade to Neura iQ for unlimited AI chat with persistent multi-session memory, multiple simultaneous Health Plans, and real-time data sync from 100+ integrations with 360° Health Sync, alongside all other premium features.

How is Neura different from other health apps or trackers?

Neura isn’t just a tracker – it’s a smart health operating system. It pulls together your data, analyzes it in real time, and gives you proactive, science-backed recommendations tailored to your lifestyle, without the hassle of manual research or multiple apps.

Can I cancel or get a refund if I’m not satisfied?

Yes. Neura Free is free forever, and Neura IQ comes with a 7-day free trial. After upgrading, you can cancel anytime. If you’re not satisfied within 30 days, we offer a full refund—no questions asked.

How do I get started with Neura?

Simply sign up with your email to claim free early access. You can start in less than 2 minutes, connect your wearables later, and immediately receive your personalized plan and first mini-podcast.

Ready to Transform
Your Health with Neura?

Don't wait, we have limited spots for the beta sign up