Resveratrol for Heart and Healthy Aging: Antioxidant Polyphenol, Endothelial Support, Daily Dosing
Overview
Resveratrol is a polyphenol from grape skin and Japanese knotweed. People use it for antioxidant backup, endothelial function, and general heart health routines. Effects are modest and depend on dose, product quality, and consistency.
Some heart routines also include Coenzyme Q10.
What Resveratrol is and how it works
Resveratrol (especially the trans form) is positioned to support antioxidant defenses and nitric oxide signaling in vessel lining. Most supplements use Polygonum cuspidatum extract. It is not a stimulant; changes, if any, are subtle over weeks.
What you may notice
Cardiovascular support
Often used to support endothelial function and a healthier lipid profile alongside diet, steps, and sleep.
Antioxidant routine
Background helper during busy blocks or travel when recovery and nutrition are dialed.
Metabolic tilt
Some users note steadier post meal feel when paired with fiber and movement.
Safety, dosing and who should skip it
Typical dosing
Common range is 100 to 300 mg trans-resveratrol per day with food. Some use up to 500 mg short term. Follow your label.
Side effects
Usually mild: GI upset, nausea, headache. Higher doses can loosen stool. Reduce or take with a larger meal if sensitive.
Drug interactions
Use caution with anticoagulants/antiplatelets and medications processed by liver enzymes. If you are on multiple prescriptions, review timing with a clinician.
Product quality
Choose third party tested products that state trans-resveratrol mg, source (e.g., Polygonum cuspidatum), and test for emodin and heavy metals. Avoid proprietary blends that hide dose.
